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Encyclopedia Britannica - Main :: MOS-NAN |
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MYXOEDEMA (or athyrea) , the medical term
condition appearing in early childhood. There are two forms, myxoedema proper and operative myxoedema (cachexia slrumipriva). (1) Myxoedema has been termed " Gull 's Disease" from Sir William Gull 's observations in 1873. Women are more often the victims than men, in a ratio of 6 to 1. It frequently affects members of the same family and may be transmitted through the mother
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appearance of skin which does not pit on pressure, the line of the features becoming obliterated and getting coarse and broad, the lips thick and nostrils enlarged, with loss of hair , subnormal temperature and marked mental changes. There is striking slowness of thought and action, the memory becomes defective, and the patient becomes irritable and suspicious. In some instances the condition progresses to that of dementia. The thyroid gland itself is diminished in size, and may become completely atrophied and converted into a fibrous mass. The untreated disease is progressive, but the course is slow and the symptoms may extend over 12 to 15 years, death from asthenia or tuberculosis being the most frequent ending. (2) Symptoms similar to the above me y follow complete removal of the thyroid gland. Kocher of Bern found that, in the total
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