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Encyclopedia Britannica - Main :: INV-JED |
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ISOXAZOLES , monazole chemical compounds corresponding to furfurane, in which the -CH group
atom is replaced by a nitrogen atom, and therefore they contain H C = N the ring system
HC =CH by the elimination of water from the monoximes of 0- diketones
ketones
RCOCH2COR+H2N .OH =2H20+RC = N HC=C-R W. Dunstan and T. S. Dymond (Jour. Chem. Soc., 1891, 49, p. 410) have also prepared isoxazoles by the action of alkalis on nitroparaffins, but have not been able to obtain the parent
stable
case
place and nitriles are formed. The isoxazoles are feebly basic.The isoxazolones are the keto derivatives of the as yet unknown 'dihydroisoxazole, and are compounds of strongly acid nature, decomposing the carbonates of the alkaline earth metals and forming salts with metals and with ammonia
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