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Encyclopedia Britannica - Main :: CLI-COM |
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COCAINE, C17H21NO4 , an alkaloid occurring to the extent of about 1% in the leaves of Erythroxylon coca
It is associated with many other alkaloids: cinnamyl cocaine, C19H23NO4; a-truxilline (C19H23N04)2; /3-truxilline, (C19H23N04)2; benzoylecgonine, C,6H,9NO2; tropa-cocaine, C13H19NO2; hygrine, C8H15NO; cuscohygrine, C,3H24NO2. These substances, which may be collectively termed " cocaines," are all derivatives of ecgonine
ecgonine
alcohol
bitter
taste , alkaline reaction, and is laevorotatory. Its use as a local anaesthetic (see ANAESTHESIA
coca
anaesthesia
accommodation . The conversion of the mixture obtained by extracting coca-leaves into cocaine is effected by saponifying the esters into ecgonine and the respective acids, and then benzoylating and methylating the ecgonine. Homologues of cocaineethylbenzoylecgonine, &c. have been prepared; they closely resemble natural cocaine. Cinnamyl cocaine is cinnamylmethylecgonine, i.e. cocaine in which the benzoyl group is replaced by the cinnamyl group. a- and fl-truxillines, named from their isolation
alcohol
diphenyl
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