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Encyclopedia Britannica - Main :: ARN-AUD |
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ATROPHY (Gr. It- priv., rpo4, nourishment) , a term in medicine used to describe a state of wasting due to some interference with the function
PATHOLOGY
work
supply and proper assimilation of nutritive material. It is also essential for the maintenance of health that a due relation exist between these processes of waste and repair, so that the one may not be in excess of the other. When the appropriation of nutriment exceeds the waste, hypertrophy (q.v.) or increase in bulk of the tissues takes place. When, on the other hand, the supply of nutritive matter is suspended or diminished, or when the power of assimilation is impaired, atrophy or wasting is the result. Thus the whole body
ATTA 877 part of the frame
change . Atrophy may, however, affect single organs or parts of the body
function
birth
standing
liver and kidneys. Parts that are subjected to continuous pressure are liable to become atrophied, as is sometimes seen in internal organs which have been pressed upon by tumours or other morbid growths, and is well illustrated in the Chinese practice of foot-binding. Atrophy may manifest itself simply by loss of substance; but, on the other hand, it is often found to co-exist with degenerative changes in the textures affected and the formation of adventitious growth, so that the part may not be reduced in bulk although atrophied as regards its proper structure. Thus, in the case of the heart, when affected with fatty degeneration, there is atrophy of the proper muscular texture, but as this is largely replaced by fatty matter, the organ may undergo no diminution in volume, but may, on the contrary, be increased in size. Atrophy is usually a gradual and slow process, but sometimes it proceeds rapidly. In the disease known by the name of acute yellow atrophy of the liver , that organ undergoes such rapidly destructive change as results in its shrinking to half, or one-third, of its normal size in the course of a few days. The term progressive muscular atrophy (synonyms, wasting or creeping palsy) is applied to an affection of the muscular system, which is characterized by the atrophy and subsequent paralysis of certain muscles, or groups of muscles, and is associated with morbid changes in the anterior roots of the nerves of the spinal cord. This disease begins insidiously, and is often first observed to affect the muscles of one hand, generally the right. The attention of the sufferer is first attracted by the power of the hand becoming weakened, and then there is found to be a wasting of certain of its muscles, particularly those of the ball of the thumb. Gradually other muscles in the arms and legs become affected in a similar manner, their atrophy being attended with a corresponding diminution in power. Although sometimes arrested, this disease tends to progress, until in course of time the greater part of the muscular system is implicated and a fatal result ensues.End of Article: ATROPHY (Gr. It- priv., rpo4, nourishment) If you wish, you can link directly to this article.
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